CHROMATOGRAPHIC STUDY AND BEHAVIOURAL STUDY OF KSHIRBALA TAILA

Abstract

Kshirbala taila is a known Ayurvedic remedy for Rheumatoid Arthritis. Its basic physico-chemical evaluation profile is reported in Ayurvedic Pharamcopoiea of India. Detailed analysis was the objective of study. The formulation was prepared using Sida cordifolia roots, sesame oil and cow milk according to literature. The formulation was then subjected to various chemical investigations. Unsaponifiable matter was studied for preliminary phytochemical screening and chemoprofiling of expected phyto-constituents using chromatographic techniques. TLC confirmed presence of sesamin, b-sitosterol, lupeol and ephedrine presence. The pre and post treatment behavioral studies were also studied and reports revealed that pain induced stress symptoms are severe in untreated arthritic rats while treated rats show significantly less frequency of occurrence compared to negative control group.