ANTIMICROBIAL ASSAY AND 4, 6 - DIPHENYL- 3, 4-DIHYDROPYRIMIDINE-2(H)-ONE
Pyrimidine is a heterocyclic aromatic organic compound similar to benzene and pyridine, containing two nitrogen atoms at positions 1 and 3 of the six-member ring. It is isomeric with two other forms of diazine. The pyrimidine skeleton is of great importance to chemists as well as biologists as it is available in a large variety of naturally occurring compounds and in clinically useful molecule having diverse biological activities. Two general method are usually employed, the cylinder-plate (or cup-plate) method and the turbidimetric (or tube assay) method. The antifungal activity performed by either in vitro or in vivo methood.
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