ANTI-CANCER PROPERTIES OF HERBS : A REVIEW

Naveen Garg; Amit Bhargava

doi:10.61280/tjpls.v9i4.92

Authors

Naveen Garg B N University, Udaipur
Amit Bhargava B N University, Udaipur

DOI:

https://doi.org/10.61280/tjpls.v9i4.92

Keywords:

Carcinogenic; Anti cancer; Herbal drugs; Medicinal plants; Apoptosis

Abstract

There are tremendous reserves of organic compounds found in many plants on Earth that only a very small amount of which as an anti-cancer compounds tested and used. Worldwide endeavors are underway to discover new anti-cancer drugs. Nowadays, there is a proclivity to use of traditional and herbal medicines in cancer treatment. The omission of this paper aimed to investigate the medicinal plants which are endemic in many parts of the world and were used for the treatment of various cancers. The evaluated plants and consequently appropriated ones that are used in cancer treatment as well as metabolites that are extracted from which would be useful to scholars around the world.

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Author Biography

Naveen Garg , B N University, Udaipur

Research Scholar

References

Dhanamani M, Devi SL, Kannan S (2011)Ethnomedicinal plants for cancer therapy- a review.Hygeia J D Med 3: 1-10.

Safarzadeh E, Sandoghchian S, Baradaran B (2014) Herbal medicine as inducers of apoptosis in cancer treatment. Adv Pharm Bull4: 421-427.

Pal SK, Shukla Y (2003) Herbal medicine: current status and the future. Asian Pac J Cancer Prev4:281-288.

Koehn FE, Carter GT (2005) The evolving role of natural products in drug discovery. Nat Rev Drug Discov 4:206-220.

Saklani A, Kutty SK (2008) Plant-derived compounds in clinical trials. Drug Discov Today 13:161-171.

Wang CZ, Calway T, Yuan CS (2012) Herbal medicines as adjuvants for cancer therapeutics. Am J Chin Med 40:657-669.

Kumar DR, George VC, Suresh PK, Kumar RA (2012) Cytotoxicity, apoptosis induction and anti-metastatic potential of Oroxylumindicum in human breast cancer cells. Asian Pac J Cancer Prev 13:2729-2734.

Wang Z, Wang N, Chen J, Shen J (2012) Emerging glycolysis targeting and drug discovery from chinese medicine in cancer therapy. Evid Based Complement Alternat Med.

Mukherjee AK, Basu S, Sarkar N, Ghosh AC (2001) Advances in cancer therapy with plant based natural products. Curr Med Chem 8:1467-1486.

Cragg GM, Newman DJ (2005) Plants as a source of anti-cancer agents. J Ethnopharmacol 100:72-79.

Ravindranath MH, Muthugounder S, Presser N, Viswanathan S (2004) Anticancer therapeutic potential of Soy isoflavonegenistein. In Complementary and Alternative Approaches to Biomedicine, Springer, US, pp: 121-165.

Liu RH (2004) Potential synergy of Phytochemicals in cancer prevention, mechanism of action. J Nutr 134: 3479S-3485S.

Kumar RA, Sridevi K, Kumar NV,Nanduri S, Rajagopal S (2004) Anticancer and immunostimulatory compounds from Andrographispaniculata. J Ethnopharmacol 92: 291-295.

Mothana R, Grunert R, Lindequist U, Bednarski PJ (2007) Study of the anticancer potential of Yemeni plants used in folk medicine. Pharmazie62: 305-307.

God JM, Tate P, Larcom LL (2007) Anticancer effects of four varieties of muscadine grape. Med Food 10: 54-59.

Zhang H, Wang X, Chen F, Androulakis XM, Wargovich MJ (2007) Anticancer activity of limonoid from Khayasenegalensis. Phytother Res 21: 731-734.

Widodo N, Kaur K, Shrestha BG, Takagi Y, Ishii T, et al. (2007) Selective killing of cancer cells by leaf extract of Aswagandha: identification of a tumour-inhibitory factor and the first molecular insights to its effects. Clin CancerRes 13: 2298-2306.

Wang SY, Feng R, Bowmank L, Lu Y, Ballington JR, et al. (2007) Antioxidant activity of Vacciniumstamineum;exhibition of anticancer capability in human lung and leukemia cells. Planta Med 53: 451-460.

Neto CC (2007) Cranberry and its phytochemicals:a review of in vitro anticancer studies. J Nutr 137: 186S-193S.

Wang MY, Su C (2001) Cancer preventive effect of Morindacitrifolia. AcadSci 952: 161-168.

Guruvayoorappan C, Kuttan G (2007) Immunomodulatory and antitumour activity ofBiophytumsenstivium extract. Asian Pac J Cancer Prev 8: 27-32.

Ferguson PJ, Kurowska EM, Freeman DJ, Chambers AF, Koropatnick J (2006) Invivo inhibition of growth of human tumour lines by flavanoid from cranberry extract. Nutur Cancer56: 86-94.

Roy MK, Kobori M, Takenaka M, Nakahara K, Shinmoto H, et al. (2007)Antiproliferative effect on human cancer cell lines after treatment nimbolide extracted from an edible part of the neem tree. Phytother Res 21: 245-250.

Arulkumaran S, Ramprasath VR, Shanthi P, Sachdanandam P (2006) Restorative effect of Kalpaamrutha, an indigenous preparation, anoxidative damage in mammary gland mitochondrial fraction in experimental mammary carcinoma. Mol Cell Biochem 291: 77-82.

Amirghofran Z, Bahmani H, Azadmehr A, Javidnia K (2006) Induction of apoptosis in leukemia cell lines by Linumpersicum and Euphorbia cheiradenia. J Cancer Res ClinOncol 132: 427-432.

Jeune ML, Kumi-Diaka J, Brown J (2005) Anticancer activities of pomegranate extracts and genistein in human breast cancer cells. J Med Food 8: 469-475.

Malikovia J, Swaczynova J, Kolar Z, Strnad M (2007) Anticancer and antiproliferative activity of natural brassinosteroids. Phytochemistry69: 418-426.

Natesan S, Badami S, Dongre SH, Godavarthi A (2007) Antitumor activity and antioxidant status of the methanol extract of Careyaarborea bark against Dalton’s lymphoma ascites induced ascetic and solid tumor in mice. J PharmacolSci 103: 12-23.

Rajkapoor B, Jayakar B, Murugesh N (2004) Antitumor activity of Indigoferaaspalathoides on Ehrlisch ascites carcinoma in mice. Indian J Pharmacol 36: 38-40.

Shoemaker M, Hamilton B, Dairkee SH, Cohen I, Campbell MJ (2005) Invitro anticancer activity of twelve Chinese medicinal herbs. Phytother Res 19: 649-651.

Dongre SH, Badami S, Godavarthi A (2008) Antitumor activity of Hypericumhookeranium against DLA induced tumor in mice and its possible mechanism of action. Phytother Res 22: 23-29.

Badisa RB, Badisa VL, Walker EH, Latinwo LM (2007) Potent cytotoxic activity of Saururuscernuus on human colon and breast carcinoma cultures under normoxic conditions. Anticancer Res 27: 189-193.

Faried A, Kurnia D, Faried LS, Usman N, Miyazaki T, et al. (2007) Anticancer effects of gallic acid isolated from Indonesian herbal medicine, PhaleriamacrocarpaBoerl, on human cancer cell lines. Int J Oncol 30: 605-614.

Shukla Y, Singh M (2007) Cancer preventive properties of ginger: a brief review. Food ChemToxicol 45: 683-690.

Amirghofran Z, Bahmani M, Azadmehr A, Javidnia K (2005) Anticancer effects of various Iranian native medicinal on humantumor cell lines. Neoplasma 53: 428-433.

Wang W, Zhao Y, Rayburn ER, Hill DL, Wang H,et al. (2007)Invitro anti-Cancer and structure activity relationships of natural products isolated from fruits of Panax ginseng. Cancer ChemotherPharmacol 59: 589-601.

Sullivan R, Smith JE, Rowan NJ (2006) Medicinal mushrooms and cancer therapy: translating a traditional practice in to western medicine. PerspectBiol Med 49: 159-170.

Zhao Y, Wang CM, Wang BG, Zhang CX (2005) Study on the anticancer activities of the Clematis manshricasaponinsinvivo. China journal of Chinese materiamedica 30: 1452-1453.

Xu M, Cui J, Fu H, Proksch P, LinW, et al. (2005)Embelin derivatives and their anticancer activity through microtubule disassembly. Planta Med 71: 944-948.

Modzelewska A, Sur S, Kumar SK, Khan SR (2005) Sesquiterpenes: natural products that decrease cancer growth. Curr MedChem Anticancer Agents 5: 477-499.

Lee JY, HwangWI, Lim ST (2004) Antioxidant and anticancer activities of organic extracts from platycodongrandiflorum A De candolle roots. J of Ethonopharmacology 93: 409-415.

Rosangkima G, Prasad SB (2004) Antitumour activity of some plants from meghalaya and mizoram against murine ascites dalton's lymphoma. Indian J of ExpBiol 42: 981-988.

Lellau TF, Liebezeif G (2003) Cytotoxic and antitumour activities of ethanolic extracts ofsalt marsh plants from lower saxonianwadden sea, Southern North sea. PharmaceuticalBiology 41: 293-300.

Rambir Singh, Bodhisattwa Maiti, BP Nagori (2011), “Recent trends in herbal drugs: a review”, International Journal of Drug Research and Technology, Volume 1,Issue,1,Pages 17-25.

Singh Rambir and Nagori B.P. (2017), “Design, synthesis, characterization and evaluation of benzoxazole derivatives for their antihyperglycaemic activitye”, Pharmacophore, 8(1), 43-53.

Dufour D, Pichette A, Mshvildadze V, Hebert ME, Lavoie S, et al. (2007)Antioxidant,Anti-inflammatory and Anticancer activities of methanolic extracts from LedumgroenlandicumRetzius. J Ethnopharmacol 111: 22-28.

Jagetia G, Rao SK (2006)Evaluation of the antineoplastic activity of guduchiTinosporacordifolia in Ehrlich ascites carcinoma bearin mice. Biological and Pharmaceutical Bulletin 29:460-466.

Rambir, Singh; BP, Nagori and Navneet, Aggarwal (2013), “Synthesis and Antimicrobial Activity of Some New Schiff’s Bases and 4- Oxothiazolidine Derivatives of 2-Mercaptobenzoxazole”,Pharmacophore, Vol. 4 (1), 10-14.

Singh, R. (2019). Medicinal Plants Used In The Treatment Of Kidney, Urinary And Gallstone (Renal Stone And Herbal Treatment): A Review. International Journal of Pharmaceutical Research and Medicinal Plants, 2(1).