Formulation and Evaluation of Emulgel of Justicia Gendarussa Leaves

Abstract

Topical drug delivery is the delivery of drugs anywhere in the body through skin, vaginal, ophthalmic and rectal routes. Drugs may be given for localized or systemic effects. Only a narrow range of drugs are available for topical use because most drugs are hydrophobic in nature and this restricts their permeation and absorption into the skin. Herbal remedies have been used in the treatment of various diseases including skin diseases for centuries and are gradually becoming acceptable as treatment options however, they are mostly hydrophobic. Emulgel has a dual control and a sustained release pattern. Emulgel improves bioavailability as well as patient compliance. The pH, viscosity, particle size, zeta potential, drug content, stability study, skin irritation test, and other properties of the prepared formulation are evaluated. The prepared herbal emulgel was evaluated for pH, spreadability, viscosity, consistency, appearance, color, washability and appearance. The proposed research work concludes that the newly formulated herbal emulgel loaded with extract of Justicia Gendarussa can be used in future for anti-inflammatory effect.