Extraction, Isolation, Phytochemical Profiling, and Biological Evaluation of Root Extracts of Aquilaria malaccensis
DOI:
https://doi.org/10.61280/tg66e205Keywords:
Aquilaria malaccensis, Antibacterial, Antioxidant, Anthelmintic activitiesAbstract
Aquilaria malaccensis is a medicinally valuable plant traditionally used in various systems of medicine to manage a wide range of ailments. This study focuses on the extraction, isolation, and phytochemical screening of ethanol and methanol root extracts of A. malaccensis to investigate their potential biological activities and identify bioactive phytoconstituents. Preliminary phytochemical screening was carried out to identify the presence of major classes of bioactive constituents is flavonoids, alkaloids, glycosides, and steroids. Isolation of phytoconstituents was performed using suitable chromatographic techniques, and the isolated compounds were characterized by IR, 1H NMR, and Mass analytical methods. The phytochemical analysis revealed that flavonoids are the main constituent in both the extracts, with variations in their abundance depending on the solvent used. Based on the phytochemical composition, the ethanol and methanol root extracts and isolated compounds like MAME-02 and EAME-01 were evaluated for their possible biological activities, including antibacterial, antioxidant, and anthelmintic using established in vitro methods. The results indicated that both extracts exhibited significant biological activities, with the ethanol extract showing comparatively higher efficacy in antibacterial and anthelmintic activities.
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